integration - Why do we treat differential notation as a fraction in u-substitution method

How did we come to know that treating the differential notation as a fraction will help us in finding the integral. And how do we know about its validity?
How can $\frac{dy}{dx}$ be treated as a fraction?
I want to know about how did u-substitution come about and why is the differential treated as a fraction in it?

Answer

It doesn't necessarily need to be.

Consider a simple equation $\frac{dy}{dx}=\sin(2x+5)$ and let $u=2x+5$. Then

$$\frac{du}{dx}=2$$ Traditionally, you will complete the working by using $du=2\cdot dx$, but if we were to avoid this, you could instead continue with the integral: $$\int\frac{dy}{dx}dx=\int\sin(u)dx$$ $$\int\frac{dy}{dx}dx=\int\sin(u)\cdot\frac{du}{dx}\cdot\frac{1}{2}dx$$ $$\int\frac{dy}{dx}dx=\frac{1}{2}\int\sin(u)\cdot\frac{du}{dx}dx$$ $$y=c-\frac{1}{2}\cos(u)$$ $$y=c-\frac{1}{2}\cos(2x+5)$$

But why is this? Can we prove that the usefulness of the differentiatals' sepertation is justified? As Gerry Myerson has mentioned, it's a direct consequence of the chain rule:

$$\frac{dy}{dx}=\frac{dy}{du}\frac{du}{dx}$$ $$\int\frac{dy}{dx}dx=\int\frac{dy}{du}\frac{du}{dx}dx$$ But then if you 'cancel', it becomes $$\int\frac{dy}{dx}dx=\int\frac{dy}{du}du$$ Which is what you desired.